Publications

Publications
(Total number of peer reviewed journal publications: 28, conference proceedings: 32, book chapter: 1)

Peer reviewed journals (27 papers and 1 invited review. 24 publications are affiliated with John Jay College)

Journals Impact Factors (IF) are from the Journal Citation Reports (JCR). Citations are from Google Scholar (GS).
Δ: indicates a John Jay undergraduate student. Highlighted in yellow.
║: Indicates a student in the Master of Forensic Sciences. Highlighted in grey.
*: indicates the corresponding author(s) i.e. the senior author(s).

1- Aguilar, W.Δ, Zacarias, O. Δ, Romaine, M.Δ, Proni, G., Petrovic, A. G., Abzalimov, R., Paz, M. M. & Champeil, E.* (2020). Synthesis of Oligonucleotides containing the cis-Interstrand Crosslink Produced by Mitomycins in their Reaction with DNA. Chemistry a European Journal, 26 (55), 12570-12578. Impact Factor: 5.16. Paper selected as HOT paper and selected for an inside cover. https:// doi/10.1002/chem.202003300

2-Zheng, M. Δ, Hwang, S. Δ, Snyder, T Δ, Aquilina, J. Δ, Proni. G. , Paz, M. M., Pradhan, P., Cheng, S.Y., & Champeil, E.* (2019). Synthesis of Mitomycin C and Decarbamoylmitomycin C N2 deoxyguanosine-adducts. Bioorganic Chemistry, 92, 103280-103290. Impact factor: 4.831. https://doi.org/10.1016/j.bioorg.2019.103280

3-Aguilar, W.Δ, Paz, M. M., Vargas, A.Δ, Zheng, M. Δ, Cheng, S.Y., & Champeil, E.* (2018). Interdependent sequence-selectivity and diastereoselectivity in the alkylation of DNA by decarbamoylmitomycin C. Chemistry a European Journal, 24 (50), 13278-13289. Impact Factor: 5.16. https://doi.org/10.1002/chem.201802038

4-Zacarias, O. Δ, Aguilar, W. Δ, Paz, M. M., Tsukanov, S. Δ, Zheng, M. Δ, Cheng, S.Y., Pradhan, P., & Champeil, E.* (2018). Isolation and rationale for the formation of isomeric decarbamoylmitomycin C-N6-deoxyadenosine adducts in DNA. Chemical Research in Toxicology, 31 (8), 762-771. Impact Factor: 3.184. https://doi.org/10.1021/acs.chemrestox.8b00102

5-Cheng, S. Y.*, Vargas, A.Δ, Lee, J. -Y. Δ, Clement, C. C.*, & Champeil, E.* (2018). Involvement of Akt in mitomycin C and its analog triggered cytotoxicity in MCF-7 and K562 cancer cells. Chemical Biology and Drug Design, 92 (6), 2022-2034. Impact Factor: 2.328. https://doi.org/10.1111/cbdd.13374

6-Aguilar, W.Δ, Paz, M. M., Vargas, A.Δ, Clement, C. C., Cheng, S.Y., & Champeil, E.* (2018). Sequence-dependent diastereospecific and diastereodivergent crosslinking of DNA by decarbamoylmitomycin C” Chemistry a European Journal, 24 (23), 6030-6035. Impact factor: 5.16. https://doi.org/10.1002/chem.201705771

7-Napolitano, T. Δ, Cheng, S.Y., Nielsen, B. Δ, Choi, C. Δ, Aguilar, W. Δ, Paz, M.M., Sapse, A.M., & Champeil, E.* (2017). Acetone promoted 1,4-migration of an alkoxycarbonyl group on a syn-1,2-diamine. Tetrahedron Letters, 58 (7), 597-601. Impact factor: 2.275. https://doi.org/10.1016/j.tetlet.2016.12.047

8-Cheng, S. Y.*, Seo, J.Δ, Huang, B.T.Δ, Napolitano, T.Δ, & Champeil, E.* (2016). Mitomycin C and decarbamoyl mitomycin C induce p53-independent p21WAF1/CIP1 activation. International Journal of Oncology, 49 (5), 1815-1824. Impact factor: 3.899. https://doi.org/10.3892/ijo.2016.3703

9-Bose, A., Surugihalli, C., Pande, P., Champeil, E., & Basu A. K.* (2016). Comparative error-free and error-prone translesion synthesis of the N2 -2'-deoxyguanosine adducts formed by mitomycin C and its metabolite, 2,7-diaminomitosene, in human cells. Chemical Research in Toxicology, 29 (5), 933-939. Impact factor: 3.432. https://doi.org/10.1021/acs.chemrestox.6b00087

10-Champeil, E.* , Cheng, S. Y.*, Huang, B.T.Δ, Conchero-Guisan, M., Martinez, T. Δ, Paz, M.M., & Sapse, A.M. (2016). Synthesis of Mitomycin C and Decarbamoylmitomycin C N2 deoxyguanosine-adducts. Bioorganic Chemistry, 65, 90-99. Impact factor: 4.831. https://doi.org/10.1016/j.bioorg.2016.02.003

11-Mouzi, L., Adams, O.║, Cuff, G., Lukasiewicz, E.Δ , Champeil, E., & Atchabahian, A.* (2016). Plasma concentrations of ropivacaine following ultrasound-guided or nerve-stimulator-guided femoral nerve block: A prospective randomized study. Anaesthesia Critical Care and Pain Medicine, 35 (1), 45-48. Impact factor: 2.707. https://doi.org/10.1016/j.accpm.2015.08.002

12-Champeil, E.* , & Sapse, A.M (2014). Synthesis of a mitomycin C-lexitropsin hybrid. Comptes Rendus Chimie, 17 (12), 1190-1196. Impact factor: 2.380. https://doi.org/10.1016/j.crci.2014.03.004

13-Champeil, E.* , Paz, M. M., Lukasiewicz, E.Δ , Kong, W.Δ, Watson, S.Δ, & Sapse, A.M. (2012). Synthesis of a major mitomycin C DNA adduct via a triaminomitosene. Bioorganic and Medicinal Chemistry Letters, 22 (23), 7198-7200. Impact factor: 2.572. https://doi.org/10.1016/j.bmcl.2012.09.052

14-Lesar, C.T. ║, Decatur, J., Luckasiewicz, E.Δ, & Champeil, E.* (2011). Identification of gamma-hydroxybutyric acid (GHB) and gamma-butyrolactone (GBL) in beverages using NMR and the PURGE solvent-suppression technique. Forensic Science International, 212 (1-3), 40-45. Impact factor: 2.108. https://doi.org/10.1016/j.forsciint.2011.06.017

15-Sapse, D., Champeil, E.* , & Sapse, A.M. (2011). Theoretical calculations applied to the study of the energetics of reactions of methamphetamine synthesis and to the characterization of reactants, products and by-products. Comptes Rendus Chimie, 14 (5), 503-510. Impact factor: 2.308. https://doi.org/10.1016/j.crci.2010.09.001

16-Invited review: Bargonetti, J., Champeil, E. , & Tomasz, M.* (2010). Differential toxicity of DNA adducts of mitomycin C. Journal of Nucleic Acids, https://doi.org/10.4061/2010/698960

17-Weng, M.-W., Zheng, Y., Jasti, V.P., Champeil, E. , Tomasz, M., Wang, Y., Basu, A. K., & Tang, M.-S* (2010). Repair of mitomycin C mono- and interstrand cross-linked DNA adducts by UvrABC: a new model. Nucleic Acid Research, 38 (20), 6976-6984. Impact factor: 11.501. https://doi.org/10.1093/nar/gkq576

18-Liu, J.║, Proni, G., & Champeil, E.* (2010) Identification and quantitation of 3,4-methylenedioxy-N-methylamphetamine (MDMA, ecstasy) in human urine by 1H NMR spectroscopy. Application to five cases of intoxication. Forensic Science International, 194 (1-3), 103-107. Impact factor: 2.108. https://doi.org/10.1016/j.forsciint.2009.10.022

19-Champeil, E.* , Proni,G., & Sapse, D. S. (2009) Ab Initio studies of receptor interactions with AMPA ((S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl) propionic acid) and kainic acid (2S-(2α, 3β, 4β))-2-carboxy-9-(1-methylethenyl)-3-pyrrolidineacetic acid. Journal of Molecular Modeling, 15 (9), 1109-1117. Impact factor: 1.507.
https://doi.org/10.1007/s00894-009-0460-y

20-Paz, M. M., Ladwa, S., Champeil, E. , Tang, L.-Q., Rockwell, S., Boamah, E., Bargonetti-Chavarria, J., Callahan, J., Roach, J., & Tomasz, M.* (2008) Mapping DNA adducts of mitomycin C and decarbamoyl mitomycin C in cell lines using liquid chromatography/ electrospray tandem mass spectrometry. Chemical Research in Toxicology, 21 (12), 2370-2378. Impact factor: 3.432. https://doi.org/10.1021/tx8002615

21-Sapse, D. S., Champeil, E. , Maddaluno, J., Fressigné, C., & Sapse, A. M.* (2008) Ab initio study of the interaction of DNA fragments with methyllithium. Comptes Rendus Chimie, 11 (10), 1262-1270. Impact factor: 2.308.
https://doi.org/10.1016/j.crci.2008.04.009

22-Champeil, E.* , Paz, M. M., Ladwa, S., Clement, C., Zatorski, A., & Tomasz, M.* (2008) Synthesis of an oligodeoxyribonucleotide adduct of Mitomycin C by the postoligomerization method via a triamino mitosene. Journal of the American Chemical Society, 130 (29), 9556-9565. Impact factor: 14.612. https://doi.org/10.1021/ja802118p

23-Champeil, E. , Crean, C., Larraya, C., Pesticelli, G., Proni, G., & Ghosez, L.* (2008) Functionalization of C60 via organometallic reagents. Tetrahedron, 64 (45), 10319-10330. Impact factor: 2.233. https://doi.org/10.1016/j.tet.2008.08.017

24-Champeil, E. , Pradham, P., & Lakshman, M. K.* (2007) Palladium-catalyzed synthesis of nucleoside adducts from bay and fjord region diol epoxides. Journal of Organic Chemistry, 72 (14), 5035-5045. Impact factor: 4.335. https://doi.org/10.1021/jo070204z

25-Champeil, E. , & Draper, S. M.* (2001) Ferrocenylalkynes as ligands in transition metal complexes. Journal of the Chemical Society, Dalton Transactions, 9, 1440-1447. Impact factor: 4.174. https://doi.org/10.1039/B008803J

26-Draper, S. M.*, Delamesiere, M., Champeil, E. , Twamley, B., Byrne, J. J., & Long, C. (1999) Novel acetylene-linked di-cobalt and tetra-cobalt carbonyl clusters” Journal of Organometallic Chemistry, 589 (2), 157-167. Impact factor: 2.304. https://doi.org/10.1016/S0022-328X(99)00399-X

27-Braga, D., Draper, S. M., Champeil, E. , & Grepioni, F.* (1999) Inorganic-organometallic crystal synthesis. The role of charge-assisted C-H…O and C-H…Cl hydrogen bonds in crystalline [(C5H5)2Co][H2PO4].3H2O and [(C6H5Me)2Cr][Cl]. Journal of Organometallic Chemistry, 573 (1-2), 73-77. Impact factor: 2.304. https://doi.org/10.1016/S0022-328X(98)00620-2

28-O’Callaghan, C. N., McMurry, T. B. H.*, Draper, S. M., & Champeil, E. (1999) Nitrile and non-nitrile pyridine products from the reaction of 2-cyano-3-(X-nitrophenyl)prop-2-enamides with methyl 3-oxobutanoate. Journal of chemical research (S), 12, 690-691. Impact factor: 0.620. https://doi.org/10.1039/A906059F

Book Chapter

Champeil, E. (2012). Magnetic resonance spectroscopy: a powerful tool for the identification and quantitation of drugs and drugs of abuse in biofluids. In D. Sapse & L. Kobilinsky (Eds), Forensic Science Advances and Their Application in the Judiciary System (pp.113-131). Boca Raton, FL: CRC press, Taylor and Francis group.

Papers Presented/Proceedings from Conferences (32):
All papers presented below have gone through a review process:

1- Clement, C., Cheng, S.-Y., Dzieciatkowska, M., Aguilar, W.Δ, & Champeil E. (2020, June). Label free pharmacoproteomic assays enabled the discovery of cellular pathways involved in the survival of MCF7 and K567 cancer cells. Paper presented at the 68th national meeting of the American Society for Mass Spectrometry, Houston, TX, (USA), in the proceedings of the American Society for Mass Spectrometry, abstract ID number 302991. ASMS.

2-Clement, C., Cheng, S.-Y., Dzieciatkowska, M., Aguilar, W.Δ, & Champeil E. (2018, June). Label free proteomics profiling of MCF7 and K562 cancer cells treated with mitomycin C and decarbamoyl mitomycin C. Paper presented at the 66th national meeting of the American Society for Mass Spectrometry, San Diego, CA, (USA), in the proceedings of the American Society for Mass Spectrometry, abstract ID number 295603. ASMS.

3-Vargas, A. Δ, Lee, J.-Y. Δ, Champeil, E. , & Cheng, S-Y. (2018, March). AKT involvement in p21 activation Induced by Mitomycin C and its analog. Paper presented at the 57th national meeting of the Society Of Toxicology, San Antonio, TX, (USA), in the proceedings of the Society of Toxicology annual meeting abstract supplement, abstract ID number 2474. SOT.

4-Clement, C., Cheng, S.-Y., Dzieciatkowska, M., Aguilar, W.Δ, & Champeil, E. (2017, December). Label free proteomics profiling of MCF7 and K562 cancer cells treated with mitomycin C and decarbamoyl mitomycin C identifies main cellular networks leading to inhibition of tumor cell proliferation. Paper presented at the annual meeting of the American Society for Cell Biology and European Molecular Biology Organization, Philadelphia, PA, (USA), in the proceedings of the American Society for Cell Biology and European Molecular Biology Organization (pp. 18), abstract ID number P1310-B317. ASCB/EMBO.

5-Aguillar, W.Δ, & Champeil, E. (2017, August). Regioselectivity of decarbamoylmitomycin C DNA monoalkylation. Paper presented at the 254th national meeting of the American Chemical Society, Washington, DC, (USA), in the proceedings of the American Chemical Society, abstract ID number MEDI-194. ACS.

6-Zacarias, O.Δ, & Champeil, E. (2017, August). Novel DNA adducts formed by decarbamoylmitomycin C at N6 of deoxyadenosine. Paper presented at the 254th national meeting of the American Chemical Society, Washington, DC, (USA), in the proceedings of the American Chemical Society, abstract ID number MEDI-311. ACS.

7-Seo, J., Huang, B.T., Cheng, S.-Y, & Champeil, E. (2016, March). P53 independent activation of p21 in response to Mitomycin C and Decarbamoylmitomycin C. Paper presented at the 55th national meeting of the Society Of Toxicology, New Orleans, LA, (USA), in the proceedings of the Society Of Toxicology, abstract ID number 1316. SOT.

8-Champeil, E. , Cheng, S. H., Huang, B.T.Δ, & Seo, J.Δ (2015, April). The role of p21 in the toxicity of mitomycin C and decarbamoylmitomycin C. Paper presented at the 106th national conference of the American Association for Cancer Research, Philadelphia, PA (USA), In Cancer Research 75 (15 Suppl) (pp. 2453), abstract ID number 2453. AACR.

9-Hsieh, V. ║, Juzovic, Z., Petraco, N., & Champeil, E. (2017, February). Discrimination of soil organic matter via nuclear magnetic resonance (NMR) spectroscopy combined with interval extended canonical variate analysis (iECVA). Paper presented at the 69th national meeting of the American Academy of Forensic Sciences, New Orleans, LA, (USA), in the proceedings of the American Academy of Forensic Sciences 23 (pp. 478), abstract ID number B163. AAFS.

10-Huang, B.T.Δ, Seo, J.Δ, Cheng, S. H., & Champeil, E. (2015, February). Synthesis of mitomycin C and decarbamoylmitomycin C interstrand cross links. Role of p21 in their toxicity. Paper presented at the 15th Gordon Research conference on mammalian DNA repair, Ventura, CA, (USA). In the interest of promoting the presentation of unpublished and frontier-breaking research, Gordon Research conferences do not permit publication of meeting proceedings.

11-Atchabahian, A., Mouzi, L., Adams, O.║, Cuff, G., & Champeil, E. (2014, June). Plasma concentrations of ropivacaine following ultrasound-guided or nerve-stimulator-guided femoral nerve block: A prospective study. Paper presented at the annual conference of the European Society of Anaesthesiology, Stockholm, (Sweden), In European Journal of Anaesthesiology, 31 (52 Suppl) (pp. 140), abstract ID number 8AP5-7. ESA, Lippincott Williams & Wilkins. Impact factor: 3.570.

12-Champeil, E. , Lesar, C.║, Decatur, J., & Lukasiewicz, E.Δ (2011, March). Report on the analysis of common beverages spiked with gamma-hydroxybutyric acid (GHB) and gamma-butyrolactone (GBL) in beverages using NMR and the PURGE solvent-suppression technique. Paper presented at the 241st national meeting of the American Chemical Society Anaheim, CA, (USA), in the proceedings of the American Chemical Society, abstract ID number ANYL-192. ACS.

13-Patrick-Saunders, L.Δ, & >Champeil, E. (2011, March). Microwave assisted methods for C-6 and C-2 modifications of 2'-deoxyguanosine. Paper presented at the 241st national meeting of the American Chemical Society, Anaheim, CA, (USA), in the proceedings of the American Chemical Society, abstract ID number ORGN-468. ACS.

14-Lukasiewicz, E.Δ , Kong, W.Δ, & Champeil, E. (2011, March). Synthesis of mitomycin C mono adducts via a post-oligomerization method. Paper presented at the 241st national meeting of the American Chemical Society, Anaheim, CA, (USA), in the proceedings of the American Chemical Society, abstract ID number ORGN-461. ACS.

15-Adams, O.║, Atchabahian, A., & Champeil E. (2011, March). Determination of local anesthetic levels after a peripheral nerve block by HPLC. Paper presented at the 241st national meeting of the American Chemical Society, Anaheim, CA, (USA), in the proceedings of the American Chemical Society, abstract ID number ANYL-43. ACS.

16-Champeil, E. (2010, December). Detection of drugs of abuse in beverages and human urine. Paper presented at the annual American Chemical Society regional meeting, Long Island section, Nassau Community College, Garden City, NY, (USA). ACS.

17-Proni, G., Tan, N., Wilson, D. K. ║, Champeil E., & Levine, B. S. (2010, August). Nuclear magnetic resonance (NMR) based study of post-mortem urines of opioid overdosed patients: Scope and limitation of the technique. Paper presented at the 240th national meeting of the American Chemical Society Boston, MA, (USA), abstract ID TOXI-125. ACS.

18-Weng, M.-W., Zheng, Y., Jasti, V. P., Champeil, E. , Tomasz, M., Wang, Y., Basu, A. K., & Tang M.-S. (2010, April). UvrABC excision of interstrand crosslink mitomycin C-DNA lesion induces double-stranded DNA breaks. Paper presented at the 101st national conference of the American Association for Cancer Research, Washington, DC, (USA), In Cancer Research 70 (8 Suppl) (pp. 1967), abstract ID number 1967. AACR.

19-Champeil, E. , Liu, J.║, Decatur, J., & Proni G. (2010, March). Identification and quantitation of 3,4-methylenedioxy-N-methylamphetamine (MDMA, ecstasy) in human urine by 1H NMR spectroscopy. Application to five cases of intoxication. Paper presented at the 239th national meeting of the American Chemical Society, San Francisco, CA, (USA), in the proceedings of the American Chemical Society, abstract ID ANYL-199. ACS.

20-Champeil, E. , Liu, J.║, Decatur, J., & Proni G. (2010, February). NMR analysis of 3,4-methylenedioxy-N-methylamphetamine (MDMA, ecstasy) and its metabolites in Urine. Paper presented at the 62nd national meeting of the American Academy of Forensic Sciences, Seattle, WA, (USA), in the proceedings of the American Academy of Forensic Sciences 16 (pp. 460), abstract ID number K36. AAFS.

21-Lesar, C.║, & Champeil E. (2009, March). Detection of club drugs (gamma hydroxybutyric acid and gamma butyrolactone) in drinks by NMR spectroscopy. Paper presented at the 35th meeting of the Northeastern Association of Forensic Scientists, Long Branch, NJ, (USA). NEAFS.

22-Liu, J.║, & Champeil E. (2009, March). Detection of drugs of abuse (ecstasy) in human urine by NMR spectroscopy” Paper presented at the 35th meeting of the Northeastern Association of Forensic Scientists, Long Branch, NJ, (USA). NEAFS.

23-Champeil, E. , Wilson, D. K. ║, & Proni, G. (2009, February). A nuclear magnetic resonance based study of urine samples containing drugs of abuse: Scope and limitations of the technique. Paper presented at the 61st national meeting of the American Academy of Forensic Sciences, Denver, CO, (USA), in the proceedings of the American Academy of Forensic Sciences 15 (pp. 419), abstract ID number K54. AAFS.

24-Champeil, E. , Paz, M. M., & Tomasz, M. (2009, March). Synthesis of two stereoisomeric deoxyribonucleoside adducts of mitomycin C. Paper presented at the 237th national meeting of the American Chemical Society, Salt Lake City, UT, (USA), in the proceedings of the American Chemical Society, abstract ID ORGN-019. ACS.

25-Champeil, E. , Wilson, D.║, & Proni G. (2008, August). Use of NMR spectroscopy for the detection of opioids in human fluids. Paper presented at the 236th national meeting of the American Chemical Society, Philadelphia, PA, (USA), in the proceedings of the American Chemical Society, abstract ID ANYL-368. ACS.

26-Champeil, E. , Paz M. M., & Tomasz M. (2008, May). Synthesis of an oligodeoxyribonucleotide adduct of mitomycin C by the postoligomerization method, via a triamino mitosene. Paper presented at the 40th middle atlantic regional meeting of the American Chemical Society, Queensborough Community College, Oakland Gardens, NY, (USA), abstract ID MRM-021. ACS.

27-Proni, G., Wilson, D.║, & Champeil E. (2008, May). Detection of opioids in urine by NMR spectroscopy. Preliminary studies. Paper presented at the 40th middle atlantic regional meeting of the American Chemical Society, Queensborough Community College, Oakland Gardens, NY, (USA), abstract ID MRM-016. ACS.

28-Tregar, K.║, Champeil, E. , & Proni, G. (2007, March). A review of forensic science programs in the United States. Paper presented at the 33rd meeting of the Northeastern Association of Forensic Scientists, Bolton Landing, NY, (USA). NEAFS.

29-Champeil E., & Tomasz M. (2006, September). Synthesis of DNA-mitomycin C adducts formed at N2 of guanine. Paper presented at the 232nd national meeting of the American Chemical Society, San Francisco, CA, (USA), in the proceedings of the American Chemical Society, Abstract ID AEI-073. ACS.

30-Champeil, E. , Paz, M. M, Clement, C. C., Zatorski, A., Ladwa, S., & Tomasz M. (2006, April). Novel Synthesis of DNA-mitomycin C adducts formed at N2 of guanine. Paper presented at the 97th national conference of the American Association for Cancer Research, Washington, DC, (USA), In Cancer Research 66 (8 Suppl) (pp. 1231), abstract ID 5249. AACR.

31-Hilmer, J.H., Champeil, E. , & Lakshman M.K. (2005, August). Carbon-carbon cross coupling reactions of 6-chloropurine nucleosides at room temperature” Paper presented at the 230th national meeting of the American Chemical Society, Washington, DC, (USA), in the proceedings of the American Chemical Society, abstract ID ORGN-412. ACS.

32-Champeil E., & Lakshman M.K. (2004, August). Synthesis of deoxyadenosine adducts of benzo[c]phenanthrene and benzo[a]pyrene” Paper presented at the 228th national meeting of the American Chemical Society, Philadelphia, PA, (USA), in the proceedings of the American Chemical Society, abstract ID ORGN-462. ACS.